Table 1:
Incidence of hospital acquisition of target multidrug-resistant organisms
| Standard disinfection period (reference group) |
UV period | Bleach period | Bleach and UV period | |
|---|---|---|---|---|
| All target organisms | ||||
| Exposed admissions | 73 071 | 81 621 | 78 760 | 81 158 |
| Incident cases (%) | 626 (0.86%) | 683 (0.84%) | 671 (0.85%) | 701 (0.86%) |
| Patient days | 345 484 | 397 222 | 382 388 | 401 822 |
| Incidence (per 10000 patient days) | 18.1 | 17.2 | 17.5 | 17.4 |
| Risk difference (95% CI) | 1 (ref) | 0.93 (−0.83 to 2.68) | 0.57 (−1.21 to 2.35) | 0.67 (−1.12 to 2.46) |
| Relative risk (95% CI); p value | 1 (ref) | 0.89 (0.79 to 1.00); 0.052 | 0.92 (0.79 to 1.08); 0.32 | 0.99 (0.89 to 1.11); 0.89 |
| Clostiidium difficile | ||||
| Exposed admissions | 76 099 | 84 776 | 82 193 | 84 741 |
| Incident cases (%) | 375 (0.49%) | 389 (0.46%) | 362 (0.44%) | 389 (0.46%) |
| Patient days | 372 654 | 426 157 | 411 471 | 436 330 |
| Incidence (per 10 000 patient days) | 10.1 | 9.13 | 8.80 | 8.92 |
| Risk difference (95% CI) | 1 (ref) | 0.93 (−0.31 to 2.18) | 1.27 (0.005 to 2.53) | 1.15 (−0.13 to 2.43) |
| Relative risk (95% CI); p value | 1 (ref) | 0.89 (0.80 to 0.99); 0031 | 0.91 (0.75 to 1.10); 0.32 | 0.97 (0.84 to 1.12); 0.68 |
| Meticillin-resistant Staphylococcus aureus | ||||
| Exposed admissions | 74 273 | 82 773 | 80 008 | 82 576 |
| Incident cases (%) | 204 (0.27%) | 259 (0.31%) | 234 (0.29%) | 242 (0.29%) |
| Patient days | 360 268 | 411 857 | 397 959 | 420 338 |
| Incidence (per 10 000 patient days) | 5.66 | 6.29 | 5.88 | 5.76 |
| Risk difference (95% CI) | 1 (ref) | −0.63 (−1.63 to 0.37) | −0.22 (−1.21 to 0.77) | −0.10 (−1.08 to 0.89) |
| Relative risk (95% CI); p value | 1 (ref) | 1.08 (0.89 to 1.30); 0.42 | 0.97 (0.76 to 1.24); 0.82 | 1.00 (0.87 to 1.14); 0.97 |
| Vancomycin-resistant enterococci | ||||
| Exposed admissions | 76 125 | 84 733 | 81 910 | 84 466 |
| Incident cases (%) | 121 (0.16%) | 138 (0.16%) | 189 (0.23%) | 194 (0.23%) |
| Patient days | 373 306 | 427 099 | 409 366 | 432 599 |
| Incidence (per 10 000 patient days) | 3.24 | 3.23 | 4.62 | 4.48 |
| Risk difference (95% CI) | 1 (ref) | 0.010 (−0.77 to 0.79) | −1.38 (−2.21 to −0.54) | −1.24 (−2.06 to −0.42) |
| Relative risk (95% CI); p value | 1 (ref) | 0.56 (0.31 to 0.996); 0.048 | 0.87 (0.65 to 1.17); 0.35 | l.28 (0.94 to l.73); 0.11 |
| Multidrug-resistant Acinetobacter spp* | ||||
| Exposed admissions | 62 773 | 71 840 | 68 486 | 70 249 |
| Incident cases (%) | 6 (0.01%) | 3 (0.00%) | 4 (0.01%) | 3 (0.00%) |
| Patient days | 331 711 | 382 680 | 365 424 | 388 748 |
| Rate (per 10 000 patient days) | 0.18 | 0.08 | 0.11 | 0.08 |
| Risk difference (95% CI) | 1 (ref) | 0.10 (−0.07 to 0.28) | 0.07 (−0.12 to 0.26) | 0.10 (−0.07 to 0.28) |
*
No models were created for multidrug-resistant Acinetobacter baumanii given the few numbers of outcomes observed in each study group; one hospital was excluded because of missing data.