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. 2019 Apr 26;2(4):e192523. doi: 10.1001/jamanetworkopen.2019.2523

Table 3. Association of Oral Infections With Carotid Artery Intima-Media Thickness in 2007.

Sign of Oral Infection Dependent Variable: Third Tertile of Mean IMT in 2007, RR (95% CI)
All Participants Boys Girls
Age- and Sex-Adjusted P Value Multivariatea P Value Age-Adjusted P Value Multivariatea P Value Age-Adjusted P Value Multivariatea P Value
Bleeding on probing and periodontal pockets
Either 1.19 (0.96-1.48) .12 1.21 (0.97-1.50) .09 1.65 (1.19-2.29) .003 1.69 (1.21-2.36) .002 0.95 (0.70-1.28) .73 0.96 (0.71-1.30) .79
Both 1.23 (0.97-1.46) .08 1.25 (0.99-1.59) .06 1.81 (1.03-2.10) .001 1.81 (1.28-2.57) .001 0.90 (0.63-1.27) .54 0.93 (0.65-1.31) .67
Caries and fillings
Either 1.50 (1.13-1.97) .004 1.42 (1.07-1.88) .01 1.54 (1.11-2.15) .01 1.46 (1.04-2.05) .02 1.40 (0.90-2.18) .14 1.25 (0.79-1.97) .35
Both 1.54 (1.16-2.03) .003 1.46 (1.10-1.94) .009 1.56 (1.11-2.17) .01 1.49 (1.05-2.63) .02 1.47 (0.94-2.30) .09 1.30 (0.82-2.08) .27
No. of signs of oral infections
0 1 [Reference] 1 [Reference] 1 [Reference] 1 [Reference] 1 [Reference] 1 [Reference]
1-3 1.82 (1.22-2.73) .004 1.74 (1.16-2.62) .008 1.84 (1.08-3.13) .02 1.75 (1.02-3.00) .04 1.73 (0.96-3.14) .06 1.59 (0.86-2.91) .14
4 2.04 (1.35-3.09) .001 1.95 (1.28-3.00) .002 2.43 (1.42-4.15) .001 2.25 (1.30-3.89) .004 1.61 (0.86-3.00) .14 1.51 (0.80-2.85) .20

Abbreviations: IMT, intima-media thickness; RR, risk ratio.

a

In addition to age and sex, the multivariate models were adjusted for cumulative exposure to the risk factors (1980-2007) and covariates were collected in 2007 (ie, family income and smoking). The results were corrected for selection bias owing to missing data by using the inverse probability weighting. Total participants: 489 (n = 218 boys; n = 271 girls).