Table 3.

Univariate and multivariate survival analysis for colorectal cancer overall survival (OS) in the training cohort. Surveillance, epidemiology and end results 2004–12 (n = 2247)

				Univariate analysis		Multivariate analysis
	1-Year OS (%)	3-Year OS (%)	5-Year OS (%)	Log-rank χ2	P	Hazard ratio	95%CI	P
All	76.55%	41.44%	23.24%
Sex				0.12	0.727
Female	75.76	41.63	23.09
Male	77.35	41.24	23.38
Age				85.7	<0.001
18–39	86.79	52.78	34.68			Ref.
40–59	85.45	50.48	29.49			1.22	0.95–1.56	0.122
>60	68.0	32.69	16.88			2.08	1.64–2.65	<0.001
T				52.44	<0.001
T1	90.30	62.68	37.97			Ref.
T2	88.79	59.41	27.32			1.1	0.63–1.92	0.746
T3	80.16	45.25	25.93			1.26	0.78–2.04	0.347
T4	67.65	31.01	16.83			1.67	1.02–2.71	0.040
N				52.08	<0.001
N0	82.49	55.13	30.07			Ref.
N1	79.78	44.64	27.39			1.22	1.04–1.43	0.014
N2	71.32	33.18	17.13			1.55	1.33–1.81	<0.001
M				23.09	<0.001
M1a	85.41	47.87	26.92			Ref.
M1b	74.12	39.57	22.21			1.44	1.22–1.7	<0.001
CEA				21.52	<0.001
Negative	79.39	51.23	31.73			Ref.
Positive	75.63	38.30	20.46			1.35	1.19–1.54	<0.001
Grade				55.23	<0.001
Well differentiated	82.95	46.53	22.43			Ref.
Moderately differentiated	80.98	45.99	25.44			0.98	0.74–1.29	0.864
Poorly differentiated	63.76	28.61	17.50			1.36	1.02–1.82	0.035
Undifferentiated	66.93	31.62	21.68			1.3	0.87–1.93	0.197
Histology				44.24	<0.001
Other Adenocarcinoma	77.8	43.25	24.48			Ref.
Mucinous adenocarcinoma	70.66	28.09	14.23			1.2	1.01–1.44	0.042
Signet ring cell carcinoma	41.9	14.37	4.79			1.46	1–2.12	0.050
Race				8.96	0.0113
White	76.28	42.38	24.43			Ref.
Black	76.18	33.65	14.75			1.31	1.13–1.54	<0.001
Othera	79.68	43.56	23.56			0.99	0.82–1.2	0.920

^aIncluding American Indian or Alaska Native and Asian or Pacific Islander.