Table 3:
Distributions of specific gravity-corrected urinary phthalate and DINCH metabolites in ng/mL.a
| Percentiles | ||||||||
|---|---|---|---|---|---|---|---|---|
| LOD | %<LOD | GM (GSD) | N | 25th | 50th | 75th | 95th | |
| Phthalate metabolites | ||||||||
| MEP | 1.2 | 0 | 41.7 (4.6) | 756 | 13.9 | 34.3 | 103 | 642 |
| MBP | 0.4 | 0 | 9.8 (2.7) | 756 | 5.8 | 10.5 | 17 | 42.9 |
| MHBP | 0.4 | 13.6 | 1.1 (2.7) | 592 | 0.6 | 1.01 | 1.8 | 5.3 |
| MBzP | 0.3 | 0.8 | 4.8 (3.3) | 756 | 2.2 | 4.82 | 11.1 | 36.3 |
| MiBP | 0.8 | 0.9 | 7.2 (2.6) | 756 | 4.1 | 6.91 | 11.9 | 34.1 |
| MHiBP | 0.4 | 1.0 | 3.1 (2.4) | 592 | 1.9 | 2.91 | 4.73 | 13 |
| MECPP | 0.4 | 0 | 12.0 (2.2) | 756 | 7.4 | 11.4 | 17.7 | 51.3 |
| MEHHP | 0.4 | 0.1 | 6.7 (2.5) | 756 | 4.0 | 6.89 | 10.9 | 31.0 |
| MEOHP | 0.2 | 0.1 | 5.2 (2.5) | 756 | 3.0 | 5.42 | 8.63 | 22.4 |
| MEHP | 0.8 | 17.1 | 1.9 (2.7) | 756 | 1.1 | 1.91 | 3.28 | 9.3 |
| ΣDEHP | - | - | 0.1 (2.3) | 756 | 0.05 | 0.09 | 0.14 | 0.4 |
| MECPTP | 0.2 | 1.4 | 3.2 (4.3) | 592 | 1.3 | 2.66 | 6.6 | 49.6 |
| MEHHTP | 0.4 | 31.4 | 0.8 (3.4) | 592 | 0.4 | 0.7 | 1.5 | 8.5 |
| MCPP | 0.4 | 5.2 | 2.3 (3.8) | 756 | 1.0 | 1.83 | 4.44 | 31.6 |
| MCOP | 0.3 | 0 | 15.9 (3.3) | 756 | 6.6 | 13.1 | 34.1 | 129 |
| MONP | 0.4 | 0.7 | 5.3 (3.8) | 592 | 2.1 | 3.86 | 11.3 | 78.5 |
| MNP | 0.9 | 43.2 | 1.4 (3.8) | 592 | 0.5 | 1.11 | 2.66 | 18.8 |
| MCNP | 0.2 | 0 | 2.8 (2.7) | 756 | 1.4 | 2.33 | 4.2 | 18.9 |
| DINCH metabolites | ||||||||
| MHiNCH | 0.4 | 63.6 | 0.3 (2.5) | 756 | 0.2 | 0.3 | 0.5 | 1.3 |
| MCOCH | 0.5 | 67.7 | 0.4 (2.0) | 592 | 0.3 | 0.36 | 0.6 | 1.2 |
| Measured outcome biomarkers | ||||||||
| 8-iso-PGF2α | 1.0 (1.8) | 759 | 0.7 | 1 | 1.4 | 2.4 | ||
| PGF2α | 2.0 (2.1) | 759 | 1.3 | 2 | 3.2 | 7 | ||
| F2-IsoP-M | 0.6 (1.6) | 759 | 0.5 | 0.6 | 0.9 | 1.4 | ||
| Derived outcome biomarkers | ||||||||
| Enzymatic fraction of 8-iso-PGF2α | 0.2 (6.3) | 759 | 0.1 | 0.3 | 0.5 | 0.9 | ||
| Chemical fraction of 8-iso-PGF2α | 0.6 (2.2) | 759 | 0.4 | 0.6 | 1 | 2.1 | ||
a
Units for ∑DEHP are in nmol/ml. Abbreviations: DINCH, LOD, limit of detection; GM, geometric mean; GSD, geometric standard deviation.