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. 2019 Apr 26;9(5):1008–1019. doi: 10.1002/2211-5463.12635

Figure 1.

Figure 1

Antidiabetic effect of PNS on C2C12 cells and KKAy mice. (A) Glucose uptake was detected in C2C12 cells treated with PNS and presented in comparison with Insulin (Ins)+2‐DG, which was a standard cellular glucose uptake reference and normalized as 1. *P < 0.05 vs. the insulin+2‐DG group, (n = 3). (B,C) Mouse FBG (B) and mouse RBG (C) were evaluated in each group (n = 8). (D–G) ITT (D) and glucose tolerance test (OGTT) (F) were determined, and AUC of ITT (E) and OGTT (G) were calculated (n = 8). (H) HOMA‐IR was calculated (n = 7). The results are expressed as the mean ± SD. *P < 0.05 vs. C57 group, **P < 0.01 vs. C57 group, # P < 0.05 vs. KK group, ## P < 0.01 vs. KK group (Tukey's test).