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. 2019 Apr 26;15:1744806919838947. doi: 10.1177/1744806919838947

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© The Author(s) 2019

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Reduction of the microglia cells activation in the spinal cord horn of MEM-10 treatment mice after SNI. (a) Microglial immunostaining against Iba-1 in mice spinal cord dorsal horns after SNI surgery. (b) The histograms, respectively, show the quantification of ratio of immunostaining density on ipsilateral (ipsi) and control (cont) sides of dorsal spinal cord after SNI surgery (one-way ANOVA with Bonferroni post hoc, naive vs. sham, p > 0.9999; sham vs. vehicle, p = 0.0005; vehicle vs. MEM-10, p = 0.0166; sham vs. MEM-10, p = 0.9704). Naive, n = 3; sham, n = 5; vehicle, n = 11; MEM-10, n = 8. **p < 0.01, vehicle group versus sham group. ^#p < 0.05, MEM-10 group versus vehicle group. MEM: memantine.