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. Author manuscript; available in PMC: 2019 Apr 29.
Published in final edited form as: Cell Rep. 2019 Feb 26;26(9):2329–2339.e4. doi: 10.1016/j.celrep.2019.01.099

Figure 7. Primate Corticospinal Axons Regenerating into Human Neural Stem Cell Grafts Avoid Sensory Interneuronal Clusters.

Figure 7.

(A) Corticospinal axons (CST) labeled for BDA are present within neural stem graft labeled for NeuN. Nine months after grafting. Horizontal section; dotted lines indicate rostral host-graft border. Scale bar, 50 μm.

(B) BDA-labeled corticospinal axons (CST) regenerate among Prdm8-expressing (V0–2) pre-motor interneurons in grafts. Scale bar, 50 μm.

(C) Corticospinal axons (CST, red) form close appositions with the surface of Prdm8-expressing (cyan) graft neurons. Scale bar, 10 um.

(D) BDA-labeled corticospinal axon (CST) density is generally attenuated in regions of Tlx-3 sensory interneuronal clusters. Dotted lines indicate sensory interneuronal domains. Left, rostral; right, caudal. Scale bars, 100 μm.