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. 2019 Apr 26;14:2945–2959. doi: 10.2147/IJN.S199781

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© 2019 Liu et al. This work is published and licensed by Dove Medical Press Limited

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Effect of EO-AuNPs on JAK/STAT signaling-related protein expression in RAW 264.7 cells. (A) The proteins of p-JAK1, JAK1, p-STAT1, STAT1, p-STAT3, and STAT3 in LPS-stimulated RAW 267.4 cells were measured by Western blot analysis. (B–D) The band intensities for p-JAK1/JAK1, p-STAT1/STAT1, and p-STAT3/STAT3 were quantified and normalized to the corresponding value of β-actin. Densitometry data are expressed as percentage relative to the non-treated control and shown as mean ± SEM. **P<0.01, ***P<0.001 compared to the non-treated control. ^#P<0.05, ^##P<0.01, ^###P<0.001 compared to the LPS control.

Abbreviations: JAK, Janus kinase; STAT, signal transducer and activators of transcription; EO-AuNPs, Euphrasia officinalis-gold nanoparticles; LPS, lipopolysaccharide; SEM, standard error of the mean.