Figure 2. K_ATP channels control the resting membrane potential of NTS neurons.

A, diazoxide induces a fast and partially reversible hyperpolarization of neurons, as shown by a representative recording (Aa). The graphs show the summary of the diazoxide effect on membrane potential (V _m; Ab) and input resistance (R _input; Ac) of neurons. B, linear correlation between the change of V _m induced by diazoxide and the resting membrane potential (RMP) of neurons. C, linear correlation between the change of R _input induced by diazoxide and the basal R _input of neurons. DZ, diazoxide; TTX, tetrodotoxin. ^* P < 0.05; ^** P < 0.01. [Color figure can be viewed at wileyonlinelibrary.com]