Table 1.
Demographic and clinical characteristics of women with Crohn’s disease stratified by vaginal and Cesarean delivery
| Characteristic | Vaginal delivery (N = 109) |
Caesarean delivery (N = 119) |
P value |
|---|---|---|---|
| Maternal age, mean (SD), years | 32.6 (3.8) | 33.7 (4.2) | 0.04 |
| Age at IBD diagnosis, mean (SD), years | 21.9 (6.6) | 22.3 (6.7) | 0.68 |
| Gestational age at delivery, mean (SD), weeks | 38.1 (2.8) | 37.8 (2.0) | 0.37 |
| Prior IBD surgery | 49 (45%) | 43 (36%) | 0.18 |
| History of perianal disease | 7 (6%) | 52 (44%) | <0.0001 |
| Prior perianal disease surgery | 3 (3%) | 22 (18%) | <0.0001 |
| Active perianal disease during pregnancy | 1 (1%) | 22 (18%) | <0.0001 |
| Active IBD symptoms during birth admission | 15 (14%) | 34 (29%) | 0.007 |
| IBD meds during pregnancy | 43 (39%) | 66 (55%) | 0.02 |
| Maternal health problem* | 12 (11%) | 17 (14%) | 0.46 |
| Maternal chronic infection† | 1 (1%) | 5 (4%) | 0.13 |
| Prior Cesarean delivery | 3 (3%) | 46 (39%) | <0.0001 |
P value < 0.05 representing statistical significance.
* Includes preeclampsia, placenta previa, diabetes, hypertension, placental abruption and pregnancy-induced hypertension.
† Includes human immunodeficiency virus (HIV), hepatitis B and hepatitis C