Fig. 5. RvE1 activates the PLD pathway to increase [Ca2+]i in rat conjunctival goblet cells.
Cultured goblet cells were preincubated with the PLD inhibitor 1-butanol (1-but) and its negative control t-butanol (t-but), both at 0.3%, for 15 min. [Ca2+]i over time is shown in A. Change in peak [Ca2+]i is shown in B. Data are mean ± SEM from 5 independent experiments. * indicates significant difference from basal; # indicates significance from RvE1 alone.