Table 5. Virulence genotyping.
Function | Genes | Number of isolates with virulence genes (%) | p value | ||
---|---|---|---|---|---|
HC (n = 7) | CD (n = 25) | UC (n = 27) | |||
Adhesin | fimH | 7 (100) | 25 (100) | 27 (100) | - |
afa-dra | 6 (85.7) | 21 (84.0) | 22 (81.5) | 0.952 | |
sfa-foc | 4 (57.1) | 11 (44.0) | 16 (59.3) | 0.527 | |
hra | 1 (14.3) | 3 (12.0) | 5 (18.5) | 0.806 | |
eaeA | 3 (42.9) | 11 (44.0) | 13 (48.1) | 0.943 | |
Invasin | ibeA | 0 (0.0) | 4 (16.0) | 4 (14.8) | 0.532 |
tia | 6 (86.0) | 19 (76.0) | 21 (77.8) | 0.860 | |
ipaH | 2 (28.6) | 15 (60.0) | 15 (55.6) | 0.331 | |
Siderophore | fyuA | 4 (57.1) | 19 (76.0) | 17 (63.0) | 0.491 |
chuA | 4 (57.1) | 16 (64.0) | 18 (66.7) | 0.894 | |
Capsule | kpsMT II | 2 (28.6) | 16 (64.0) | 14 (51.9) | 0.237 |
kpsMT I (K1) | 1 (14.3) | 9 (36.0) | 6 (22.2) | 0.385 | |
Toxin | hlyA | 7 (100) | 23 (92.0) | 26 (96.3) | 0.631 |
estA | 0 (0.0) | 0 (0.0) | 0 (0.0) | - | |
estB | 2 (28.6) | 5 (20.0) | 3 (11.1) | 0.475 | |
Protectin | ompA | 7 (100) | 25 (100) | 27 (100) | - |
Miscellaneous | pic | 7 (100) | 23 (92) | 23 (85.2) | 0.459 |
aggR | 5 (71.4) | 22 (88.0) | 25 (92.6) | 0.304 | |
yjaA | 0 (0.0) | 19 (76.0) | 13 (48.1) | 0.001 | |
tsp | 5 (71.4) | 14 (56.0) | 17 (63.0) | 0.731 |
HC, healthy control; CD, Crohn’s disease; UC, ulcerative colitis