Table 3.
Univariable and multivariable cox regression of factors associated with death from all causes (n = 50)
| Univariable | Multivariable | |||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age | ||||
| <60 | 1.00 | 1.00 | ||
| 60‐69 | 1.65 (0.56‐4.86) | 0.367 | 1.06 (0.29‐3.91) | 0.934 |
| 70‐79 | 1.34 (0.48‐3.71) | 0.573 | 1.05 (0.32‐3.46) | 0.942 |
| 80‐89 | 0.47 (0.16‐1.43) | 0.185 | 0.46 (0.12‐1.83) | 0.272 |
| >=90 | 0.58 (0.17‐1.97) | 0.386 | 1.19 (0.20‐7.07) | 0.850 |
| Gender | ||||
| Male | 1.00 | 1.00 | ||
| Female | 0.72 (0.40‐1.30) | 0.278 | 0.63 (0.31‐1.26) | 0.189 |
| ECOG | ||||
| 1 | 1.00 | 1.00 | ||
| 2 | 1.29 (0.71‐2.36) | 0.405 | 1.67 (0.86‐3.25) | 0.131 |
| 3 | 2.61 (0.87‐7.84) | 0.089 | 1.32 (0.26‐6.67) | 0.738 |
| 4 | 15.24 (1.64‐141.35) | 0.017 | 4.74 (0.42‐53.61) | 0.208 |
| T stage | ||||
| <T4 | 1.00 | 1.00 | ||
| T4 | 1.27 (0.69‐2.33) | 0.441 | 0.94 (0.43‐2.03) | 0.867 |
| Disease status | ||||
| Locally advanced (M0) | 1.00 | 1.00 | ||
| Metastatic (M1) | 2.32 (1.14‐4.75) | 0.021 | 3.70 (1.05‐13.07) | 0.042 |
| Nodal positivity | ||||
| No (N0) | 1.00 | 1.00 | ||
| Yes (N1) | 0.92 (0.44‐1.92) | 0.830 | 0.49 (0.19‐1.27) | 0.141 |
| Chemotherapy | ||||
| None | 1.00 | 1.00 | ||
| Before RT | 3.82 (1.38‐10.54) | 0.010 | 1.88 (0.41‐8.69) | 0.420 |
| After RT | 0.87 (0.38‐1.98) | 0.737 | 0.76 (0.25‐2.36) | 0.641 |
| Bleeding response to RT | ||||
| No | 1.00 | 1.00 | ||
| Yes | 0.20 (0.09‐0.44) | <0.001 | 0.20 (0.07‐0.57) | 0.003 |
ECOG, Eastern Cooperative Oncology Group; HR, hazard ratio; CI, confidence interval; RT, radiotherapy.