Figure 3.

CDKN2B‐AS1 contributed to invasion and migration of HeLa cells by inhibiting miR‐181a‐5p. Cells were divided into four groups: Ctrl, sh‐CDKN2B‐AS1, miR‐181a inhibitor, sh‐CDK +inhibi inhibitor. (A) The invasion abilities of HeLa cells were detected by Boyden Chamber Transwell assays. The cell invasion abilities were quantified. Mean cell counts from at least 10 fields and data represent the mean ± SD of triplicate determinations from three separate experiments and compared using the unpaired t test. (B) The migration abilities of HeLa cells were detected by wound healing assays. HeLa cells scraped by a pipette tip were cultured for 24 h. A representative of wound healing assay was presented. **P < 0.01, compared with Ctrl group. ^## P < 0.01, compared with miR‐181a inhibitor group