Skip to main content
. 2019 Apr 11;43(6):2440–2450. doi: 10.3892/ijmm.2019.4163

Figure 5.

Figure 5

Effects of glucose on TXNIP expression and activation of NLRP3 inflammasome in HK-2 cells at different times. Cells were incubated with 50 mmol/l glucose for 0, 24, 48, 72 and 96 h. (A) Western blots and (B) quantified expression levels of TXNIP, NLRP3, cleaved-caspase-1 and caspase-1 proteins at different time points. (C) IL-1 and (D) IL-18 expression levels were detected by ELISA. *P<0.05 and **P<0.01, vs. control (0 h) group; #P<0.05 and ##P<0.01. TXNIP, thioredoxin interacting protein; NLRP3, NOD-like receptor protein 3; IL, interleukin.