Skip to main content
. 2019 Apr 15;43(6):2352–2360. doi: 10.3892/ijmm.2019.4167

Figure 5.

Figure 5

GRB7 overexpression abolishes the inhibitory effect of miR-193a-3p on the oncogenic capacity of breast cancer. (A) Western blotting and (B) statistical analysis of the overexpression of GRB7 which abolished the decrease of GRB7 due to overexpression of miR-193a-3p in HER2 positive breast cancer cells. *P<0.05 and **P<0.01, as indicated. (C) Cell vitality was significantly increased. **P<0.01. (D) The colony formation capacity was significantly promoted. **P<0.01, as indicated. (E) Cell invasion and (F) migration abilities were significantly accelerated by GRB7 overexpression. *P<0.05 and **P<0.01. GRB7, growth factor receptor bound protein 7; NC, negative control; OD, optical density; miR, microRNA.