Table 2.
Univariate and multivariate analyses of prognostic factors for 5‐y survival of 436 patients (409 with complete covariate information)
| Characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| Odds Ratio [95% CI] | P value | Odds Ratio [95% CI] | P value | |
| Gender | ||||
| Female | 1 | |||
| Male | 0.445 [0.22‐0.89] | 0.0224 | ‐ | ‐ |
| Age at metastasis stage (y) | ||||
| ≤ 55 | 1 | |||
| > 55 | 0.291 [0.14‐0.6] | 0.0009 | 0.229 [0.1‐0.5] | 0.0002 |
| PS at metastasis stage | ||||
| 0 | 1 | |||
| 1 | 0.490 [0.23‐1.04] | |||
| ≥2 | 0.100 [0.01‐0.77] | 0.0240 | ‐ | ‐ |
| Histology | ||||
| Synovial sarcoma | 1 | |||
| Endometrial stromal sarcoma | 26.656 [2.63‐270.5] | |||
| Leiomyosarcoma | 0.502 [0.16‐1.56] | |||
| Liposarcoma | 0.314 [0.07‐1.34] | |||
| Others | 0.500 [0.17‐1.43] | |||
| UPS | 0.267 [0.08‐0.93] | 0.0031 | ‐ | ‐ |
| Sarcoma genomics | ||||
| Simple genomic sarcoma | 1 | |||
| Complex genomic sarcoma | 0.437 [0.22‐0.85] | 0.0143 | ‐ | ‐ |
| Size of tumor | ||||
| ≤5 cm | 1 | |||
| >5 cm | 0.424 [0.2‐0.88] | 0.0211 | ‐ | ‐ |
| Grade of tumor | ||||
| 1 | 1 | 1 | ||
| 2 | 0.138 [0.06‐0.35] | 0.125 [0.05‐0.33] | ||
| 3 | 0.081 [0.03‐0.2] | <0.0001 | 0.065 [0.02‐0.17] | <0.0001 |
| Liver metastasis | 1 | |||
| No liver metastasis | 3.417 [1.03‐11.36] | 0.0450 | ‐ | ‐ |
| DFI (mo) | ||||
| ≤24 | 1 | |||
| >24 | 2.528 [1.25‐5.10] | 0.0096 | ‐ | ‐ |
DFI, disease‐free interval; PS, Performance status; UPS, Undifferentiated pleomorphic sarcoma.