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. Author manuscript; available in PMC: 2019 Apr 29.
Published in final edited form as: Nat Microbiol. 2018 Sep 3;3(10):1142–1152. doi: 10.1038/s41564-018-0238-z

Figure 3. Tse6tox-EF-Tu-Tsi6 subcomplex is highly flexible.

Figure 3.

(a) Representative 2-D class averages showing diffuse densities for the Tse6tox-EF-Tu-Tsi6 subcomplex. White arrows indicate flexible region (see also Supplementary Video 1). Scale bar: 10 nm.

(b) Schematic representation of flexibility of the Tse6tox-EF-Tu-Tsi6 subcomplex, which is connected to the more rigid VgrG1-Tse6NTD-EagT62 subcomplex by a linker.

(c) Rotated views and cross-sections of filtered 3-D average (green) and 3-D variability (yellow) densities corresponding to the VgrG1-Tse6-EagT62-EF-Tu-Tsi6 complex. The variability density indicates the range of positions taken by the Tse6tox-EF-Tu-Tsi6 subcomplex. Structures of VgrG1 (green), Tse6PAAR (yellow) and EagT6 (red) are fitted in 3-D average volume for orientation.

See also Supplementary Tables 2 and 3 and Supplementary Video 1.