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. 2019 Apr 5;8:e42475. doi: 10.7554/eLife.42475
Parameter Unit Description
KD = koff/kon nM Dissociation constant of PhyB ON-PIF-TCR complex (darkness)
Q = qon/qoff Association constant of multivalent binding step (darkness)
τD,PhyB = ln(2)/koff s Half-life of PhyB ON-PIF-TCR complex (darkness)
γoff = qoff/koff Distinction of off-rates of mono- and multivalent dissociation
I 0 Intensity at which ki = koff
τ KPR s Duration of KPR mechanism (=threshold half-life of the ligand-TCR interaction)