Parameter | Unit | Description |
---|---|---|
KD = koff/kon | nM | Dissociation constant of PhyB ON-PIF-TCR complex (darkness) |
Q = qon/qoff | – | Association constant of multivalent binding step (darkness) |
τD,PhyB = ln(2)/koff | s | Half-life of PhyB ON-PIF-TCR complex (darkness) |
γoff = qoff/koff | – | Distinction of off-rates of mono- and multivalent dissociation |
I 0 | – | Intensity at which ki = koff |
τ KPR | s | Duration of KPR mechanism (=threshold half-life of the ligand-TCR interaction) |