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. Author manuscript; available in PMC: 2019 Apr 29.
Published in final edited form as: J Org Chem. 2016 Oct 13;81(20):9560–9566. doi: 10.1021/acs.joc.6b00922

Table 1.

Serum IgG Subclass Anti-rHagB Activity at Day 42a

entry adjuvant IgG1 (μg/mL) IgG2a (μg/mL) IgG2a/IgG1
1 none 264.6 ± 30.3 9.7 ± 2.8 0.036 ± 0.007
2 GPI-0100 756.4 ± 39.33d 327.2 ± 70.2c 0.5 ± 0.1c
3 2x 546.2 ± 41.7b 24.2 ± 6.3 0.04 ± 0.01
4 3x 950.5 ± 90.5d 380.0 ± 72.9d 0.40 ± 0.06b
5 4x 813.3 ± 88.8d 495.9 ± 65.2d 0.7 ± 0.1d
6 5x 460.7 ± 28.0 4.5 ± 0.8 0.010 ± 0.002
a

Values are the mean ± SEM.

b

P < 0.05.

c

P < 0.01.

c

P < 0.001.