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. Author manuscript; available in PMC: 2020 May 20.
Published in final edited form as: Free Radic Biol Med. 2019 Mar 26;136:12–21. doi: 10.1016/j.freeradbiomed.2019.03.026

Figure 2. Lack of metabolic stress and sensitization to other DNA-damaging drugs after Asc loading.

Figure 2.

Treatments with drugs were for 3 h in panels A, D, E and for 1 h in panels B and C. Data are means ±SD, n=3. (A) Normal levels of ATP in DHA-preincubated H460 and A549 cells. (B) AMPK phosphorylation in control and DHA-preincubated cells treated with high or (C) low doses of BLM. (D) Colony formation by H460 and A549 cells treated with doxorubicin or (E) mitomycin C without or with 0.5 mM DHA preincubation.