Table 5.

Relationship between and IL-6 and average sleep duration by rs6198 genotype, controlling for lifestyle factors

	IL-6
	Model 1		Model 2		Model 3		Model 4		Model 5
Variables	β	p	β	p	β	p	β	p	β	p
Age	.051	.138	.050	.150	.043	.198	.053	.124	.044	.184
Sex	−.099	.004	−.109	.002	−.056	.097	−.092	.008	−.053	.121
Education	−.095	.006	−.086	.013	−.074	.026	−.089	.009	−.061	.067
Physical Activity			−.106	.002					−.054	.110
BMI					.271	< .001			.270	.000
Smoking							.058	.096	.083	.013
Avg Sleep	−.190	.001	−.194	.001	−.142	.011	−.186	.001	−.138	.014
rs6198	.057	.094	.054	.113	.060	.068	.058	.089	.059	.072
rs6198*Avg Sleep	−.123	.033	−.118	.038	−.105	.059	−.119	.037	−.098	.074
F	5.91	< .001	6.55	< .001	14.58	< .001	5.57	< .001	12.44	< .001
R2	0.041		0.053		0.110		0.045		0.121
tdiff			0.043	.965	0.221	.825	0.044	.965	0.25	.802

Notes: Age & Education in years; Sex: 0 = male, 1 = female; Physical Activity (kCal/week); BMI (kg/m²); Smoking (Y: current smoker; N: never smoker, tried it, ex-smoker); Avg Sleep = weighted average of weeknight and weekend sleep duration (hours); Avg sleep is mean centered in all models; rs6198: a glucocorticoid receptor SNP with an A to G substitution. ‘rs6198’ is coded as 1 (GG), 0 (AG), and −1 (AA).