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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: J Am Acad Child Adolesc Psychiatry. 2018 Oct 29;58(9):876–886.e2. doi: 10.1016/j.jaac.2018.09.431

Table 3.

Comparison of Diagnostically- and Empirically-Driven Latent Class Analysis (LCA) and Other Best-Fitting Models in a Subsample Whose Autism Spectrum Disorder (ASD) Diagnoses Were Available

Model fit index values

Models k LL BIC
ELCA 25 −9929.562 20046.830
CLCA 25 −12014.234 24216.173
EFMAa 71 −9344.797 19222.680
LCFAb 45 −9449.843 19237.560
LCFAc 27 −12014.230 24231.190
CFAd 28 −9446.573 19103.376
Items LCA item endorsement probabilities
CFAd factor loadings
ELCA CLCA
High ASD Low ASD ASD Non-ASD SI COM RRB
(44.71) (55.29) (46.96) (53.04)
Relates to others in an unusual way .652 .067 .528 .149 .831 -
Difficulty playing with and relating to other children .783 .089 .633 .188 .941 - -
Lack of interest in making friends .447 .039 .371 .087 .810 - -
Lacks interest in or awareness of other people’s feelings .447 .065 .349 .133 .737 - -
Language difficulties .516 .055 .404 .131 - .844 -
Difficulty engaging in socially appropriate conversation .850 .101 .696 .202 .403 .551 -
Speaks in an odd way .411 .019 .331 .070 - .873 -
Difficulty engaging in make-believe play .305 .008 .245 .047 - .802 -
Is preoccupied with certain topics .647 .110 .561 .160 - - .792
Distressed by small changes in routine or environment .541 .139 .462 .189 - - .633
Engages in odd repetitive movements .421 .060 .368 .089 - - .756
Has intense interest in parts of objects .291 .016 .254 .036 - - .816

Note: Numbers in parentheses under the LCA item endorsement probabilities section represent the percentage of individuals assigned to a given ASD symptom class. BIC = Bayesian information criteria; CFA = confirmatory factor analysis; CLCA = confirmatory latent class analysis; COM = communication factor; ELCA = exploratory latent class analysis; k = number of parameters; LL = log-likelihood; RRB = restricted repetitive behavior factor. SI = social interaction factor.

Model subscripts:

a

The 2-class/2-factor model

b

The 6-class/3-factor model

c

The DSM-5-based 2-class/2-factor model

d

CFA with cross-loading of item “difficulty engaging in socially appropriate conversation”.