Table 1. Patients’ Demographic Data .
| Patients’ characteristics | Group 1 (n = 16) | Group 2 (n = 11) | Group 3 (n = 4) | P value |
| Age | 49.7 ± 11 | 28.8 ± 12.2 | 45.0 ± 13.6 | 0.54 |
| Sex | M = 14, F = 2 | M = 8, F = 3 | M = 3, F = 1 | 0.400 |
| Type of IBD | UC = 11 | UC = 6 | UC = 3 | 0.01 |
| CD = 2 | CD = 2 | CD = 1 | ||
| IC = 3 | IC = 3 | IC = 0 | ||
| Extend of disease | Pancolitis = 4 | Pancolitis = 2 | Pancolitis = 0 | 0.52 |
| Left sided = 7 | Left sided = 5 | Left sided = 2 | ||
| Proctitis = 2 | Proctitis = 2 | Proctitis = 1 | ||
| Colonic CD = 1 | Colonic CD = 1 | Colonic CD = 0 | ||
| Ileal = 0 | Ileal = 0 | Ileal = 0 | ||
| Ileo-colonic = 2 | Ileo-colonic = 1 | Ileo-colonic = 1 | ||
| Duration of disease | Mean = 13 yrs. | Mean = 11 yrs. | Mean = 9 yrs. | 0.008 |
| Hospital admission | 16 | 11 | 4 | 0.06 |
| Steroids | 16 | 11 | 4 | 0.60 |
| Thiopurine | 8 | 5 | 3 | 0.54 |
| Antibiotics | 4 | 1 | 3 | 0.24 |
| Anti TNF | 6 | 1 | 1 | 1.00 |
| 5 ASA | 12 | 9 | 3 | 0.200 |
| Cyclosporine | 3 | 0 | 1 | 1.00 |
| Positive serology | 14 | 9 | 4 | 0.001 |
| Previous surgery | 5 | 2 | 1 | 0.600 |
| Positive cytopathic changes on HE | 13 | 8 | 3 | 0.46 |
|
Colectomy (three patients with UC had colectomy without treatment with ganciclovir and were excluded) |
1 | 3 | 1 | 0.190 |
| Death | 0 | 1 | 0 | 1.00 |
| Transfusion reaction | 3 | 0 | 1 | 1.00 |
| Side effect | 3 | 1 | 1 | 0.88 |
| UC- ulcerative colitis, CD- Crohn’s disease, IC- Indeterminate colitis, TNF- tumor necrotic factor, ASA- aminosalicylic acid | ||||