Table 1.

Inhibitory activity of some coumarin derivatives (Fig. 1) against AChE and BChE.

Compound	AChE (IC50 μM)	BChE (IC50 μM)
Tacrine	0.124 ± 0.02	7.8 ± 0.06
1	875 ± 3.30	163.5 ± 4.61
2	42.5 ± 2.68	458 ± 3.30
3a	46.25 ± 3.30	1.2 ± 0.05
3b	81.5 ± 3.30	7.6 ± 0.15
3c	137 ± 5.61	367 ± 5.40
3d	216 ± 9.34	216 ± 3.05
3e	222 ± 2.41	222 ± 3.53
3f	100 ± 5.53	268 ± 3.05
3g	116 ± 3.58	233 ± 3.30
3h	24.25 ± 2.97	0.0020 ± 0.0014
4a	442 ± 3.68	442 ± 3.65
4b	135 ± 3.31	1.1 ± 0.088
4c	129 ± 3.35	3.4 ± 0.087
5	163 ± 3.40	46.7 ± 0.68