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. 2019 Apr 29;21(4):61. doi: 10.1208/s12248-019-0323-0

Fig. 2.

Fig. 2

Concentration-time profiles of observed data and model predictions in one individual (p12) for the [11C]erlotinib + erlotinib data set. Concentration-time profiles in the liver and extrahepatic bile duct/gall bladder in the baseline scan (a, b) and in the scan acquired after oral pre-treatment with unlabeled erlotinib (c, d). Observed data is represented with open black circles; modeled data is represented with colored lines (AIF, arterial input function; DIF, dual input function; 3C, three compartment; 4C, four compartment)