Table III.

Parameter Estimates of the 3C Model for the [¹¹C]Erlotinib + Rifampicin Data Set

Subject	Arterial input function			Dual input function
	k1 (min−1)	k2 (min−1)	k3 (min−1)	k1 (min−1)	k2 (min−1)	k3 (min−1)	β (min)
Baseline scan
p37	1.000 (3)	0.021 (4)	0.004 (1)	2.711 (8)	0.023 (10)	0.005 (1)	2.170 (69)
p38	2.024 (2)	0.020 (2)	0.005 (1)	4.202 (3)	0.009 (10)	0.008 (1)	0.608 (49)
p39	1.346 (1)	0.003 (10)	0.008 (1)	3.643 (5)	0.002 (30)	0.014 (1)	0.802 (40)
p40	1.994 (1)	0.001 (20)	0.007 (1)	4.456 (5)	0.0002(277)	0.007 (2)	1.342 (84)
p41	2.471 (1)	0.010 (3)	0.007 (1)	4.639 (5)	0.001 (101)	0.009 (1)	0.758 (44)
p42	1.485 (4)	0.010 (13)	0.010 (3)	4.008 (7)	0.007 (28)	0.015 (5)	0.800 (138)
Mean ± SD	1.720 ± 0.538	0.011 ± 0.008	0.007 ± 0.002	3.943 ± 0.697	0.007 ± 0.009	0.010 ± 0.004	1.080 ± 0.590
Second scan (after i.v. rifampicin)
p37	1.037 (2)	0.018 (4)	0.008 (1)	2.304 (3)	0.010 (9)	0.012 (1)	2.122 (41)
p38	1.082 (2)	0.014 (4)	0.002 (1)	2.589 (3)	0.015 (5)	0.004 (1)	0.823 (74)
p39	1.227 (3)	0.020 (4)	0.006 (1)	2.715 (3)	0.013 (9)	0.010 (2)	0.758 (56)
p40	2.016 (1)	0.012 (3)	0.003 (1)	4.422 (1)	0.009 (5)	0.004 (1)	0.797 (28)
p41	2.305 (1)	0.007 (6)	0.011 (1)	4.781 (3)	0.001 (76)	0.012 (1)	0.601 (69)
p42	1.197 (2)	0.012 (6)	0.009 (1)	2.462 (5)	0.005 (24)	0.012 (2)	0.727 (73)
Mean ± SD	1.477 ± 0.542	0.014 ± 0.005	0.007 ± 0.004	3.212 ± 1.091	0.009 ± 0.005	0.009 ± 0.004	0.971 ± 0.569

For legend to this table, see Table I legend