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. 2019 Apr 29;9:6627. doi: 10.1038/s41598-019-43004-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Examples of possible non-binders to CRM1. (A) Segments located in the ordered globular fold. (B) Segments with β-strands in the middle. (C) Segments located in the ordered region and have β-strands in the middle. The hydrophobic residues are colored in red or green in the sequences and displayed as sticks in the structures.