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. 2019 Apr 29;9:6579. doi: 10.1038/s41598-019-42972-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Mortality of procalcitonin (PCT), C-reactive protein (CRP), and their combinations. Optimal cut off of CRP elevation was defined as ≥14 mg/dL and PCT elevation was defined as ≥17 ng/mL. Overall 28-day mortality was 20.7%. The mortality rates of both CRP and PCT not elevated, only CRP elevated, only PCT elevated, and both CRP and PCT elevated were 18.1%, 21.5%, 17.8%, and 26.9%, respectively. The mortality of both CRP and PCT elevated was significantly higher than for both not elevated and only PCT elevated.