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. 2019 Apr 29;9:6638. doi: 10.1038/s41598-019-43269-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of the expression changes of differentially expressed lncRNAs, related target genes, and the correlation between them. The heatmap was generated from the fold change values in the RNA-seq data and was used to visualize the lncRNAs and cis-regulated relation target expression changes (A) and the lncRNAs and trans-regulated relation target expression changes (C). (B) The correlation between the expression changes of lncRNAs and cis-regulated relation target. The values along the x-axis are the log2fold change of lncRNAs (fold change = FPKM value of genes in the cold treatment/FPKM value of lncRNA genes in the control). The values along the y-axis are the log2fold change of their target genes in cis-regulatory relationships (fold change = FPKM value of genes in the cold treatment/FPKM value of genes in the control). (D) The correlation between the expression changes of lncRNAs and trans-regulated relation target. The values along the x-axis are the log2fold change of lncRNAs (fold change = FPKM value of genes in the cold treatment/FPKM value of lncRNA genes in the control). The values along the y-axis are the log2fold change of their target genes in trans-regulatory relationships (fold change = FPKM value of genes in the cold treatment/FPKM value of genes in the control).