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. 2019 Apr 28;5(4):e01567. doi: 10.1016/j.heliyon.2019.e01567

Fig. 4.

Fig. 4

Expression of key protein associated apoptosis, inflammation and cell-marker among different group. Note: (1) Meanings of the combination of letters and numbers in the icon: a, b, c, d, e, f are respectively represented as proteins of Bax, Bcl-2, NF-Κb, MAP-2, Olig-2 and GFAP; 1, 2, 3 are respectively represented as Sham operated Group, Model Group and MDP Group. (2)*: Compared to Model Group, P < 0.05; #: Compared to Sham operated Group, P < 0.05. Part A, C described the expression of key proteins associated apoptosis and inflammation among three groups. Expression of Bax was up-regulated in Model Group (a2), but it was inhibited by MDP (a3). For the expression of Bcl-2, the trend is completely an opposite, it was down-regulated in Model Group (b2) but boosted by MDP (b3). The trend of NF-κB is similar to that of Bax (c2, c3). Part B, D delineate the expression of cell-specific marker proteins among three groups. MAP-2 was inhibited in Model Group (d2) but encouraged by MDP (d3); For the expression of Olig-2, the trend was roughly same to MAP-2 (e2, e3); For the expression of GFAP, the trend is completely an opposite (f2, f3).