Fig. 5.

Effects of treatment with lipoproteins on Pgp expression: (1) parent cells; (2) resistant cells; (3) resistant cells exposed to oxLDL; (4) resistant cells exposed to VLDL. Data are presented as mean ± standard deviation. The T test revealed no significant differences between parent cells and resistant cells (p = 0.394), resistant cells alone and resistant cells treated with oxLDL (p = 0.059). Significant difference was observed only resistant cells alone and resistant cells treated with VLDL (p = 0.02). All experiments were performed in replicates (parent n = 4, resistant n = 13, resistant oxLDL n = 12, resistant VLDL n = 6).