Table 2.

Hemodynamic Data of WT and HMGB1-Tg Mice Following Saline or Ang II Infusion

	WT Saline (n = 14)	WT Ang II (n = 10)	HMGB1-Tg Saline (n = 15)	HMGB1-Tg Ang II (n = 10)
BW, g	25.7 ± 0.6	27.1 ± 0.6	26.3 ± 0.6	26.8 ± 0.6
Hemodynamic parameter
HR, beats/min	608 ± 17	612 ± 20	586 ± 16	615 ± 20
SBP, mm Hg	92 ± 3.3	142 ± 3.9∗	95 ± 3.2	138 ± 3.9†
DBP, mm Hg	36 ± 5.7	95 ± 6.8‡	32 ± 5.5	69 ± 6.7†
MBP, mm Hg	55 ± 4.6	111 ± 5.5∗	51 ± 4.5	92 ± 5.5†

Values are mean ± SE.

BW = body weight; DBP = diastolic blood pressure; HR = heart rate; MBP = mean blood pressure; SBP = systolic blood pressure; other abbreviations as in Table 1.

^∗p < 0.001 versus WT saline mice.

^†p < 0.001 versus HMGB1-Tg saline mice.

^‡p < 0.01versus WT saline mice.