Table 1.
High-Resolution Respirometry |
Enzyme Activity Assays |
BN-PAGE In-Gel Activity |
Cardiolipin Mass Spectrometry |
|||||
---|---|---|---|---|---|---|---|---|
Nonfailing | Failing | Nonfailing | Failing | Nonfailing | Failing | Nonfailing | Failing | |
No. of heart samples | 13 | 23 | 11 | 12 | 19 | 21 | 5 | 10 |
Male | 6 | 15 | 4 | 7 | 8 | 10 | 3 | 7 |
Female | 7 | 8 | 7 | 5 | 11 | 11 | 2 | 3 |
Age, yrs | 25 ± 7 | 31 ± 5 | 20 ± 8 | 29 ± 8 | 26 ± 5 | 25 ± 5 | 28 ± 13 | 29 ± 9 |
Ejection fraction, % | 64 ± 5 | 24 ± 2 | 64 ± 4 | 27 ± 3 | 61 ± 3 | 22 ± 6 | 58 ± 2 | 20 ± 3 |
Values are n or mean ± SEM.
BN-PAGE = blue native polyacrylamide gel electrophoresis.