Figure 2.

Impact of GLC and GLC Receptor Antagonism on Myocardial Infarction

(A) Representative hematoxylin and eosin section of cardiac tissue 4 weeks after MI treated with PBS (Control), GLC, and GLC receptor antagonist (REMD). (B) Quantification of infarct scar sizes based on histological analysis; group sizes are indicated in each bar graph. (C) Representative TUNEL staining images of left ventricle with apoptotic cells indicated by arrows. (D) Quantification of percent TUNEL-positive cells with group sizes indicated. #p < 0.01. (E) Representative trichrome staining of left ventricular tissue. (F) Quantification of fibrotic area in the noninfarcted left ventricle from each group with group sizes indicated. Abbreviations as in Figure 1.