Table 5.

Association of VKORC1 and CYP2C9 SNPs with INR Treatment Outcome.

Gene	SNP ID	Genotype	Initiation INR	P-value*	Maintenance INR	P-value*
VKORC1	rs10871454	CC	2.73 [0.58]	0.346	2.63 [0.40]	0.297
		CT	2.60 [0.40]		2.68 [0.63]
		TT	2.54 [0.65]		2.74 [0.36]
	rs8050894	CC	2.71 [0.58]	0.362	2.63 [0.39]	0.246
		CG	2.63 [0.67]		2.67 [0.39]
		GG	2.52 [0.58]		2.77 [0.38]
	rs9934438	CC	2.73 [0.58]	0.253	2.63 [0.40]	0.312
		CT	2.61 [0.67]		2.68 [0.40]
		TT	2.51 [0.57]		2.76 [0.36]
	rs17708472	CC	2.59 [0.67]	0.901	2.71 [0.41]	0.517
		CT	2.67 [0.45]		2.64 [0.33]
		TT	2.53 [0.50]		2.50 [0.17]
CYP2C9	rs1799853	CC	2.51 [0.61]	0.159	2.69 [0.38]	0.381
		CT	2.63 [0.69]		2.69 [0.42]
		TT	3.20 [0.14]		3.00 [0.0]
	rs4086116	CC	2.67 [0.61]	0.621	2.67 [0.40]	0.389
		CT	2.54 [0.63]		2.70 [0.37]
		TT	2.49 [0.73]		2.83 [0.43]
	rs1057910	AA	2.66 [0.66]	0.046	2.67 [0.40]	0.190
		AC	2.41 [0.46]		2.77 [0.35]

^*One-way ANOVA test with p-value < 0.05 is considered significant, Mean Standard deviation in square brackets.