Skip to main content
. 2019 Apr 20;24:101206. doi: 10.1016/j.redox.2019.101206

Fig. 4.

Fig. 4

Novel derivatives of vitamin D3 and lumisterol enhance the repair of 6-4 photoproducts (6-4PP). HEKn cells cultured for three days were pretreated with the indicated hydroxy-derivatives of vitamin D3 or lumisterol (100 nM), or ethanol vehicle, for 24 h before UVB irradiation at either (A) 25 mJ/cm2 or (B) 50 mJ/cm2. After irradiation, cells were further incubated in fresh media with the same hydroxy-derivative for an additional 1 or 3 h. The disappearance of 6-4 Photoproducts between 1 and 3 h was used to determine the percent repair.