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. 2019 Jan 7;27(4):463–466. doi: 10.1016/j.jsps.2019.01.008

Table 3.

Comparison of correct rate in DDIs knowledge.

Drug – drug combinations Correct answer (%) Incorrect answer (%) P value
Warfarin and cimetidine 59.7 40 0.3 <0.0001
Sildenafil and isosorbide mononitrate 74.6 25.4 <0.0001
Conjugated estrogens and raloxifen 27.2 72.8 <0.0001
Fexofenadine HCL and metoprolol 43.8 56.2 <0.0001
Theophylline and ciprofloxacin 35 65 <0.0001
Pimozide and ketoconazole 32.5 67.5 <0.0001
Methyldopa and phenobarbital 17.7 82.3 <0.0001
Phenytoin and cimetidine 30.7 69.3 <0.0001
Itraconazole and quinidine 37.8. 62.2 <0.0001
Amiodarone and simvastatin 43.1 56.9 <0.0001
Methotrexate and probenecid 21.2 78.8 <0.0001
Diphenhydramine and warfarin 30.7 69.3 <0.0001
Raloxifene and alendronate 32.3 67.8 <0.0001
Warfarin and diflunisal 37.5 62.5 <0.0001
Amiodarone and fluconazole 16.3 83.7 0.0004
Theophylline and omeprazole 34.3 65.7 <0.0001
Sulfinpyrazone and warfarin 31.4 68.6 <0.0001
Meperidine and phenelzine 44.2 55.8 <0.0001
Fluconazole and phenytoin 37.8 62.2 <0.0001
Warfarin and nortriptyline 51.6 48.4 <0.0001
Amoxicillin and acetaminophen with codeine 69.6 30.4 <0.0001
Digoxin and clarithromycin 39.9 60.1 <0.0001
Alprazolam and itraconazole 25.4 74.6 <0.0001
Dopamine and phenytoin 40.3 59.7 <0.0001
Ciprofloxacin and tizanidine 24.7 75.3 <0.0001
Cyclosporine and rifampicin 31.1 68.9 <0.0001