Table I.
Baseline characteristics of the study group
| Parameter | Study group (N = 215) | Subjects with MACCE plus CLP (n = 83) | MACCE-free subjects (n = 132) | P-value |
|---|---|---|---|---|
| Age, mean (SD) [years] | 63.3 (9.8) | 63.1 (9.2) | 61.3 (10.1) | 0.396 |
| Men, n (%) | 154 (71.6) | 59 (71) | 95 (72) | 0.888 |
| Hypertension, n (%) | 199 (93) | 81 (98) | 118 (89) | 0.026 |
| Diabetes mellitus, n (%) | 102 (47) | 42 (51) | 60 (45) | 0.462 |
| Hyperlipidemia, n (%) | 194 (90) | 76 (92) | 118 (89) | 0.601 |
| Smoking history, n (%) | 138 (64) | 57 (69) | 81 (61) | 0.276 |
| Number of cardiovascular risk factors among hypertension, hyperlipidemia, diabetes, cigarette smoking, mean (SD) | 2.93 (0.88) | 3.05 (0.78) | 2.86 (0.93) | 0.058 |
| Statin, n (%) | 210 (98) | 80 (96) | 130 (98.5) | 0.320 |
| Intermittent claudication, n (%) | 66 (31) | 31 (37) | 35 (26) | 0.093 |
| LVEF, mean (SD) % | 52.8 (10.1) | 52.7 (10.5) | 52.3 (9.9) | 0.442 |
| hsCRP, mean (SD) [g/l] | 3.12 (2.79) | 3.25 (3.38) | 3.06 (2.31) | 0.001 |
| Body mass index, mean (SD) [kg/m2] | 27.6 (3.6) | 27.2 (3.8) | 27.8 (3.4) | 0.494 |
| Creatinine, mean (SD) [µmol/l] | 93 (33.4) | 96.9 (36.7) | 90.4 (27.3) | 0.049 |
| Total cholesterol, mean (SD) [mmol/l] | 4.97 (1.31) | 5.07 (1.41) | 4.9 (1.23) | 0.486 |
| LDL cholesterol, mean (SD) [mmol/l] | 3.06 (1.1) | 3.08 (1.1) | 3.05 (1.1) | 0.255 |
| HDL cholesterol, mean (SD) [mmol/l] | 1.19 (0.33) | 1.21 (0.36) | 1.17 (0.31) | 0.277 |
| Triglycerides, mean (SD) [mmol/l] | 1.74 (1.43) | 1.97 (1.8) | 1.6 (1.1) | 0.217 |
CAD – coronary artery disease, IS – ischemic stroke, LVEF – left ventricular ejection fraction, MI – myocardial infarction.