Table II.
Multivariate stepwise Cox proportional hazards analysis. Independent risk factors of MACCE, recurrent MI and recurrent MI plus coronary lesion progression (CLP)
| Cardiovascular event | Hazard ratio | 95% confidence interval | P-value |
|---|---|---|---|
| MACCE: | |||
| Serum creatinine level | 1.01 | 1.003–1.017 | 0.006 |
| The annual CIMT progression > 0.003 mm/year | 3.00 | 1.496–6.016 | < 0.001 |
| Recurrent MI: | |||
| Serum creatinine level | 1.01 | 1.003–1.017 | 0.004 |
| Hyperlipidemia | 3.15 | 1.271–7.784 | 0.013 |
| Annual CIMT progression > 0.003 mm/year | 4.59 | 1.591–13.217 | 0.005 |
| Recurrent MI plus new angina due to CLP: | |||
| Serum creatinine level | 1.01 | 1.004–1.018 | 0.002 |
| Hyperlipidemia | 3.50 | 1.759–6.964 | 0.005 |
| Annual CIMT progression > 0.003 mm/year | 2.95 | 1.378–6.323 | < 0.001 |
CIMT – carotid intima-media thickness, CLP – coronary lesion progression, MACCE – major adverse cerebral and coronary events, MI – myocardial infarction.