Table III.
Variables associated with eGFR variation in univariate and multivariate linear regression analysis
| Parameter | Univariate analysis | Multivariate analysis (R2 = 0.11) | ||
|---|---|---|---|---|
| β (95% CI) | P-value | β (95% CI) | P-value | |
| Diabetes | –4.01 (–5.36 – –2.66) | 0.001 | –3.08 (–4.76 – –1.40) | 0.001 |
| CHA2DS2-VASc score ≥ 4 | –1.44 (–2.80 – –0.08) | 0.038 | – | NS |
| Baseline eGFR < 60 ml/min/1.73 m2 | –3.56 (–4.96 – –2.17) | 0.001 | –1.64 (–3.29 – –0.003) | 0.05 |
| Contrast volume > 150 ml | –2.67 (–4.57 – –0.77) | 0.006 | – | NS |
| ACS as clinical presentation | –1.50 (–2.86 – –0.14) | 0.031 | – | NS |
| Warfarin vs. NOAC therapy | –1.66 (–3.11 – –0.20) | 0.025 | –1.59 (–2.99 – –0.18) | 0.027 |
ACS – acute coronary syndrome, eGFR – estimated glomerular filtration rate, NOAC – non-vitamin K oral anticoagulant. Regression coefficients (β) with 95% confidence intervals (95% CI) and p-values for the univariate and multivariate analysis. R2 displayed for the multivariate model.