Figure 3.

The mean average of follicular diameter (μm) on days 0, 6, and 12 of the experiment. ^{a, b, and c} show significant differences compared with the control group, Hesp 10, and Hesp 22.5, respectively. On day 6, the administration of hesperidin at the dose of 22.5 µmol/L caused greater increase in follicular diameter in comparison with the control group (^ap < 0.05); however, in the Hesp 50 group, the mean diameter of follicles was significantly increased compared with the control, Hesp 10, and Hesp 22.5 (^ap < 0.05, ^bp < 0.05, and ^cp < 0.001, respectively). On day 12, the administration of hesperidin at the dose of 22.5 µmol/L could increase the follicular diameter in comparison with the control and Hesp 10 groups (^ap < 0.05 and ^bp < 0.05, respectively), while treatment with 50 µmol/L hesperidin (Hesp 50) caused greater increase in follicular diameter in comparison with the control, Hesp 10, and Hesp 22.5 (^ap < 0.05, ^bp < 0.05, and ^cp < 0.001, respectively). (A color version of this figure is available in the online journal.)