Figure 4.

PFT‐μ significantly reduced SCI lesion volume: A, Tissue sections from injured wild‐type mice taken at 7 and 30 dpi were stained for the astrocytic marker GFAP. Injured mice had been injected ip with either vehicle or 8 mg/kg of PFT‐μ. Sham controls underwent laminectomy without contusion. Dotted lines outline the lesion border. Scale bar = 200 μm. B, Lesion volume was quantified by an observer blind to the treatment group using ImageJ. Welch two‐sample t test, two‐sided was used to determine the significance between experimental and control groups. At 7 dpi; Vehicle n = 9, PFT‐μ n = 6. At 30 dpi; Vehicle n = 5, PFT‐μ n = 9. Data are shown as mean ± SEM *P < .05, **P < .01