Figure 5.

PFT‐μ significantly reduced the presence of microglia/macrophages in the SCI lesion site at 30 dpi: (A). Tissue sections from injured MacGreen mice were stained for Collagen IV to delineate the lesion border. Dotted lines outline the injury epicenter. Sham controls underwent laminectomy without contusion. Scale bar = 200 μm (B). The intensity of E‐GFP (microglia/macrophage) signal contained within the lesion site was quantified by an observer blind to the treatment group using ImageJ. At 7 dpi; Vehicle n = 7, PFT‐μ n = 6. At 30 dpi; Vehicle n = 4, PFT‐μ n = 8. Welch two‐sample t test, two‐sided was used to determine the significance between experimental and control groups. Data are shown as mean ± SEM. *P < .05