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HE staining (200×) verifies the successful establishment of rat models of IA. Degenerative changes were observed in the vessel wall structure of the right anterior cerebral artery/olfactory artery bifurcation and eventually an aneurysm was formed. As indicated by the arrow, internal elastic lamina is injured, and the vascular wall is expanded, and the wall of the middle cerebral artery is enlarged. IA, intracranial aneurysm; HE, hematoxylin eosin
