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. 2018 Aug 12;25(2):233–244. doi: 10.1111/cns.13043

Figure 9.

Figure 9

Map of molecular mechanisms involved in SRPK1 regulation in the apoptosis of intracranial aneurysm smooth muscle cells. SRPK1 is upregulated with a dysregulated PI3 K‐AKT signaling pathway in intracranial aneurysm. After SRPK1 gene silencing, the apoptosis of intracranial aneurysm smooth muscle cells was inhibited via the suppression of the PI3 K/AKT signaling pathway. SRPK1, SR protein‐specific kinases; PI3 K, phosphatidylinositol‐3 kinase