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Determination of C. rotundus fractions cytotoxicity (CC50), anti-HBV activity (IC50) and their corresponding therapeutic index (TI).
| C. rotundus fraction | CC50 | IC50 | TI |
|---|---|---|---|
| Hexane | 389.5 | NA | ND |
| Chloroform | 360.5 | NA | ND |
| Ethyl acetate | 470 | 46.2 | 10.17 |
| n-Butanol | 827.6 | 94.8 | 8.72 |
| Aqueous | 783.5 | 107.8 | 7.26 |
NA: no activity; ND: not determined.
