TREM-1 inhibition reduces expression of M-CSF and TREM-1 in OIR. A representative Western blot of retinal lysates from OIR mice at P17 reveals that TREM-1 blockade using GF9-HDL and GA/E31-HDL significantly suppresses expression of TREM-1 and M-CSF. The membrane was probed for TREM-1, reprobed for M-CSF and then for β-actin. Values in the bar graphs represent the mean ± SEM, n = 6. *, p < 0.05, **, p < 0.01 vs. vehicle-treated mice.