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. 2019 Apr 5;17(6):4693–4702. doi: 10.3892/etm.2019.7470

Figure 1.

Figure 1.

Downregulation of miR-153 in breast cancer. The mRNA expression level of miR-153 was determined by reverse transcription-quantitative polymerase chain reaction using tissue samples from patients with breast cancer. (A) The miR-153 expression levels were downregulated in breast cancer tissue compared with adjacent healthy tissue. **P<0.01 vs. Adjacent. (B) Patients with breast cancer with low miR-153 expression had a shorter survival time compared with patients with breast cancer with high miR-153 expression. (C) The miR-153 expression levels were downregulated in human breast cancer cell lines compared with normal human breast cell line MCF-10A. **P<0.01 vs. MCF-10A. Adjacent, adjacent healthy tissue; Breast cancer, primary breast cancer tissue; MCF-10A, normal human breast epithelial cell line; BT-549, MCF-7, MDA-MB-453, MDA-MB-231 and SK-BR-3, human breast cancer cell lines; miR, microRNA.