Table II.
Risk factors affecting disease-free survival.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Factors | HR | 95% CI | P-value | HR | 95% CI | P-value |
| Age (<45 vs. ≥45 years) | 0.81 | 0.37–1.79 | 0.603 | – | – | – |
| Sex (male vs. female) | 0.89 | 0.21–3.79 | 0.893 | – | – | – |
| Multifocality (yes vs. no) | 0.56 | 0.17–1.88 | 0.348 | – | – | – |
| TNM tumor stage (I+II vs. III) | 4.65 | 2.05–10.54 | <0.001 | 28.59 | 4.18–195.70 | 0.001 |
| LRG-1 (low vs. high) | 2.85 | 1.28–6.33 | 0.011 | 1.14 | 1.02–1.92 | 0.041 |
LRG-1, leucine-rich-alpha-2-glycoprotein 1; HR, hazard ratio; CI, confidence interval.